Posted to MedZilla HealthCare on 2/20/2019

Takeda Pharmaceuticals

US-MA, Scientis I/II R0004776-MZ


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Job Description

Sci I/II, Lead Discovery


The Lead Discovery group within ImmunoOncology Research at Takeda Boston is seeking a Cell Biologist/Immunologist with extensive cell based assay development experience to progress small/large molecule programs into the clinic. The successful candidate will also independently design and implement experiments to address mechanisms-of-action of therapeutic molecules. The research scientist will also be responsible for participating on matrix project teams, interfacing very closely with members of the Protein Sciences/Immuno Biologics/ Chemistry/IO Biology teams.


  • Provide broad assay development support for early stage drug discovery projects in the field of Oncology/IO
  • Collaborate with engineers to identify suitable approaches for assay automation and execute high throughput small molecule/large molecule screens
  • Design, execute and validate a variety of assays to understand mechanism of action of compounds and characterize different biologics
  • Contribute and implement new ideas and in vitro proof of concept studies to enable initiation and progression of early discovery projects
  • Interface with project teams to meet timelines for project progression
  • Evaluate and implement the best assay technologies in collaboration with project teams to fit the purpose at hand
  • Present research findings clearly and effectively at internal and external meetings
  • Support drug discovery programs by providing relevant scientific and strategic input to drive project decisions
  • Manage resource allocation across programs based on needs and prioritization
  • Troubleshoot complex problems in creative and effective ways and actively participates in innovation and/or optimization of established processes to ensure delivery on project goals


  • MS/PhD in Biochemistry/Cell Biology/Immunology with Post-Doc experience or 2+ years of relevant experience or equivalent, in early stage pharmaceutical drug discovery
  • Team player able to liaise across multiple disciples including Automation, Cell Biology, Chemistry, Compound Management and Immunology
  • Self-motivated, collaborative with excellent time management and organizational skills
  • Skilled in analysis, interpretation, and presentation of results
  • Experience with mammalian cell culture with best practices in tissue culture is required
  • Hands on experience with automated platforms
  • Excellent written and verbal communication skills, along with the ability to work in cross-functional project teams
  • Innovative and critical thinking
  • Ability to advance multiple projects in a fast paced environment


  • Manual dexterity required to operate office equipment (i.e., computers, phones, etc.).
  • Carrying, handling and reaching for objects up to 25 lbs.
  • Working in a lab environment: standing, walking, bending, etc.


  • Willingness to travel to various meetings or client sites, including overnight trips. Some international travel may be required.
  • Requires approximately 0-5% travel


Boston, MA

Worker Type


Worker Sub-Type


Time Type

Full time

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