Posted to MedZilla HealthCare on 7/19/2018

Takeda Pharmaceuticals

US-MA, Head of Genomics Technologies Group (Associate Director/Director) R0000573-MZ


By clicking the Apply button, I understand that my employment application process with Takeda will commence and that I agree with Takeda s Privacy Notice, Privacy Policy and Terms of Use.

Job Description

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as Head Genomics Technologies Group in our Cambridge office.

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Head Genomics Technologies Group working on the Translational and Biomarker Research team, you will be empowered to lead the implementation of genomics technologies and manage a group of scientists and a typical day will include:


The Translational and Biomarker Research (TBR) group at Takeda designs the clinical biomarker and patient characterization strategies, develops and implements clinical biomarkers assays through a network of external laboratories and delivers high quality biomarker, PK, immunogenicity and patient characterization data to support early and late stage clinical programs and reverse translation. TBR is dedicated to technical innovation for clinical application across multiple platform types and investigates novel technologies as needed for clinical goals and patient characterization. TBR biomarker strategies and clinical assays are utilized in all therapeutic areas of Takeda s focus: Neuroscience, Oncology and Gastrointestinal diseases.

We are seeking a senior leader for the Genomics Technologies group in TBR. This group is responsible for the development and implementation of nucleic acid technology platforms for clinical assays and patient characterization strategies and delivery of high quality data for clinical use and reverse translation. Working within a completely externally facing model, platform expertise includes DNA and RNA technologies to identify transcriptomic, mutational and epigenetic variations. Techniques and methods are tailored to the needs of the clinical trial utilizing nucleic acids from a variety of sources including the tumors, cfDNA, exosomes and the microbiome. Importantly, this group is responsible for technical innovation to bring new patient characterization platforms into clinical use.

The head of Genomics Technologies will lead a group of scientists to establish high level experimental plans including analysis for genomics assay development and utilization in clinical trials, oversee assay development and outsourcing to vendor labs according to the budget and timelines and deliver high quality clinical data. A key role is to identify and test emerging technologies and develop a strategy for investment and clinical implementation, especially in genetics and epigenetics.


  • Direct implementation of genomics technologies in clinical trials for patient characterization and as biomarkers, integrating technical excellence and analytical strategy
  • Manage a group of scientists to support clinical programs through the development and outsourcing of genomics assays to external vendors, ensure that clinical study timelines for data delivery are met and data is high quality and meets clinical laboratory standards and regulatory and legal requirements
  • Establish collaborations and effectively communicate TBR genomic capabilities within the global Takeda organizations to advance the use of genomics technologies for forward and reverse translation.
  • Partner with computational biologists and statisticians to establish priorities for clinical genomics data analysis, management, database build and internal and external supporting resources. Drive identification and use of innovative analytical methods based on clinical data needs
  • Subject matter expert for clinical application of genomics technologies and analytical tools
  • Drive technical innovation for patient characterization especially for epigenetic applications


  • PhD in molecular biology, computational biology, genetics or a related field, with 5+ years of experience in multiple genomics technologies and applications
  • Knowledge of human genetics and epigenetics
  • Experience in the application of genomics technologies in clinical trials
  • Experience with processing and analysis of next-generation sequencing and other genomic data
  • Knowledge of genomics applications in multiple disease areas (oncology, neuroscience and gastrointestinal) and able to articulate questions which can be answered from complex data sets
  • Proven track record of developing strategies and leading the implementation of genomics technologies that are an integral part of drug development and disease characterization
  • Experience in performing due diligence and implementing in the clinic innovative technology platforms as part of an overall technology development strategy
  • Demonstrated ability to establish effective collaborative relationships with cross functional scientific and clinical teams in a matrix environment
  • Strong communication and organizational skills
  • Supervisory experience


  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

Empowering Our People to Shine

Learn more at

No Phone Calls or Recruiters Please.


Please visit our website at


* If a direct employer requests that you go to their web site and complete your application there in order to be
  considered, please do so. Applications for all positions are subject to each employer's specific requirements.